Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Quality comparison of traditional Chuanxiong produced in Dujiangyan City and Sichuan ProvinceC and Chuanxiong from other areas, based on analysis of volatile oil, total alkaloids and total ferulic acid contents

Ling Chen¹, Jia Hou², Wei Deng¹, Guihua Jiang¹

¹Chengdu University of Traditional Chinese Medicine, Chengdu 611137; ²College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China.

For correspondence:- Guihua Jiang Email: 11469413@qq.com

Accepted: 25 November 2020 Published: 31 December 2020

Citation: Chen L, Hou J, Deng W, Jiang G. Quality comparison of traditional Chuanxiong produced in Dujiangyan City and Sichuan ProvinceC and Chuanxiong from other areas, based on analysis of volatile oil, total alkaloids and total ferulic acid contents. Trop J Pharm Res 2020; 19(12):2659-2666 doi: 10.4314/tjpr.v19i12.26

© 2020 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Purpose: To compare the qualities of Chuanxiong from different production areas (authentic and traditional production areas in Dujiangyan, Sichuan Province) and other non-authentic production areas, as well as different germplasm sources, using a combination of methods.

Methods: A fingerprint spectrum of volatile oils was established, and the qualities of the chuanxiong samples were compared using gas chromatography (GC), while gas chromatography-mass spectrometry (GC -MS) was used to analyze the chemical compositions of the volatile oils.

Results: There were significant differences in the chemical compositions of volatile oils of Chuanxiong from different plants. Most of the qualities of Chuanxiong were higher after transplantation to the germplasm nursery at Dujiangyan, Sichuan. There was increase in the contents of total alkaloids and total ferulic acid in some chuanxiong transplanted to the germplasm nursery.

Conclusion: This is the first study that compares the quality of Chuanxiong from different producing areas using a combination of several methods. These methods are feasible and effective, and the results provide a reference for research on standardization and quality control of Chuanxiong.

Keywords: Chuanxiong, Volatile oil, Total alkaloids, Ferulic acid, Fingerprint, Dujiangyan City